Detection of autoantibodies against islet amyloid polypeptide in human serum. Lack of association with Type 1 (insulin-dependent) diabetes mellitus, or with conditions favouring amyloid deposition in islets

@article{Gorus2005DetectionOA,
  title={Detection of autoantibodies against islet amyloid polypeptide in human serum. Lack of association with Type 1 (insulin-dependent) diabetes mellitus, or with conditions favouring amyloid deposition in islets},
  author={F. Gorus and J. Sodoyez and D. Pipeleers and B. Keymeulen and A. Foriers and C. F. Schravendijk and Belgian Diabetes Registry},
  journal={Diabetologia},
  year={2005},
  volume={35},
  pages={1080-1086}
}
  • F. Gorus, J. Sodoyez, +4 authors Belgian Diabetes Registry
  • Published 2005
  • Medicine
  • Diabetologia
    • SummaryA radiobinding assay for the detection of autoantibodies against islet amyloid polypeptide was developed, analytically validated, and -in parallel with a similar assay for the detection of autoantibodies against insulin — applied to sera from recent-onset Type 1 (insulin-dependent) diabetic patients and from age- and sex-matched control subjects. There was no difference in islet amyloid polypeptide autoantibody titres between patient groups and matched control subjects, nor within… CONTINUE READING
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    15 Citations
    Background Citations
    7
    Methods Citations
    1
    Results Citations
    1
    15 Citations
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    Citation Type

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    Cutting Edge: CD4 T Cells Reactive to an Islet Amyloid Polypeptide Peptide Accumulate in the Pancreas and Contribute to Disease Pathogenesis in Nonobese Diabetic Mice
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