Detection of auto-antibodies against cytochrome P4502E1 (CYP2E1) in chronic hepatitis C.

@article{Vidali2007DetectionOA,
  title={Detection of auto-antibodies against cytochrome P4502E1 (CYP2E1) in chronic hepatitis C.},
  author={Matteo Vidali and Giuseppa Occhino and Alessandra Ivaldi and Roberto Serino and Stefania Moia and Elisa Alchera and Rita Carini and Cristina Rigamonti and Massimo Sartori and Emanuele Albano},
  journal={Journal of hepatology},
  year={2007},
  volume={46 4},
  pages={605-12}
}
BACKGROUND/AIMS Chronic hepatitis C (CHC) is often associated with auto-immune reactions. In the light of the role of alcohol in promoting CHC progression, we have investigated the possible presence of auto-reactivity against the ethanol-inducible cytochrome P4502E1 (CYP2E1) in CHC patients with and without alcohol consumption. METHODS The IgG reactivity against recombinant human CYP2E1 was evaluated by solid-phase immunoassays in 102 CHC patients with different alcohol consumption and 59 HCV… CONTINUE READING

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