Detection of apoptosis in human endometriotic tissues.

  title={Detection of apoptosis in human endometriotic tissues.},
  author={Mikiko Harada and Nobuhiko Suganuma and Madoka Furuhashi and Tetsuo Nagasaka and Nariyasu Nakashima and Fumitaka Kikkawa and Yutaka Tomoda and Kumiko Furui},
  journal={Molecular human reproduction},
  volume={2 5},
To clarify whether apoptosis is involved in endometriosis, we obtained eutopic endometrial tissues along with endometriotic tissues from the uterus (adenomyosis) (n = 12) and from the ovary (n = 12) from patients undergoing gynaecological surgery. Apoptosis-induced DNA fragmentation was detected by the TdT-mediated dUTP-biotin nick-end labelling method, and immunostaining with a monoclonal antibody against the Fas, Le(y) or B-cell leukaemia/lymphoma-2 (bcl-2) was also performed using the same… CONTINUE READING


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