Detection of antigliadin antibodies in bullous diseases and their recognition of similar antigenic polypeptides.

@article{Kumar1987DetectionOA,
  title={Detection of antigliadin antibodies in bullous diseases and their recognition of similar antigenic polypeptides.},
  author={Vipan Kumar and Neena S Jain and Ernst H. Beutner and Tadeusz P. Chorzelski},
  journal={International archives of allergy and applied immunology},
  year={1987},
  volume={83 2},
  pages={155-9}
}
The presence of antigliadin antibodies (AGA) in dermatitis herpetiformis (DH) has been associated with gluten-sensitive enteropathy. Because of the discrepancies in the specificity of AGA, we examined the sera of patients with DH, pemphigus and pemphigoid for AGA both by enzyme immunoassay and by immunofluorescence. Approximately 80-90% of sera of patients with DH had AGA. AGA were not disease-specific, they also occurred in about 40-80% of patients with pemphigus and pemphigoid depending on… CONTINUE READING