Detection of antibodies against pre-S1 proteins in sera of patients with hepatitis B virus (HBV) infection.

@article{Theilmann1987DetectionOA,
  title={Detection of antibodies against pre-S1 proteins in sera of patients with hepatitis B virus (HBV) infection.},
  author={Lorenz Theilmann and Mo Quen Klinkert and K. Gmelin and Burkhard Kommerell and Eberhard Pfaff},
  journal={Journal of hepatology},
  year={1987},
  volume={4 1},
  pages={22-8}
}
Pre-S1 (large S) proteins are components of the envelope of HBV. The presence of pre-S1 proteins is correlated with viral replication. To test sera of patients with HBV infection for the presence of antibodies against pre-S1 proteins (anti-pre-S1), an E. coli extract containing a pre-S fusion protein covering the greater part of the pre-S1 region was… CONTINUE READING