Detection of antibodies against hepatitis A in blood spots dried on filter paper. Is this a reliable method for epidemiological studies?

@article{Gil1997DetectionOA,
  title={Detection of antibodies against hepatitis A in blood spots dried on filter paper. Is this a reliable method for epidemiological studies?},
  author={{\'A}ngel Gil and Angels Gonz{\'a}lez and Rafael Dal-R{\'e} and Victoria Dom{\'i}nguez and Paloma Astasio and Lorenzo Aguilar},
  journal={Epidemiology and infection},
  year={1997},
  volume={118 2},
  pages={189-91}
}
Diluted dried blood drops on filter paper were compared with serum samples as a specimen source for qualitative anti-HAV antibody determination by ELISA. A total of 298 serum samples and dried blood drops were collected from a population of healthy adolescents (15.3 +/- 1.2 years old). The prevalence of anti-HAV antibody obtained by testing serum samples was 7.7% (95% CI:4.8 10.1). Compared with serum sampling the sensitivity and specificity of diluted dried blood drops were 91.3 and 99.3%. The… CONTINUE READING

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