Detection of anthrax toxin by an ultrasensitive immunoassay using europium nanoparticles.


We developed a europium nanoparticle-based immunoassay (ENIA) for the sensitive detection of anthrax protective antigen (PA). The ENIA exhibited a linear dose-dependent pattern within the detection range of 0.01 to 100 ng/ml and was approximately 100-fold more sensitive than enzyme-linked immunosorbent assay (ELISA). False-positive results were not observed… (More)
DOI: 10.1128/CVI.00412-08

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