Detection of an immature dentate gyrus feature in human schizophrenia/bipolar patients

  title={Detection of an immature dentate gyrus feature in human schizophrenia/bipolar patients},
  author={Noah M. Walton and Yang Zhou and Jeffrey H. Kogan and Rick Shin and Maree J. Webster and Adam K. Gross and Carrie L. Heusner and Quan-fu Chen and Shinichi Miyake and Katsunori Tajinda and Kouichi Tamura and Tsuyoshi Miyakawa and Mitsuyuki Matsumoto},
  booktitle={Translational Psychiatry},
Hippocampus-associated cognitive impairments are a common, highly conserved symptom of both schizophrenia (SCZ) and bipolar disorder (BPD). Although the hippocampus is likely an impacted region in SCZ/BPD patients, the molecular and cellular underpinnings of these impairments are difficult to identify. An emerging class of mouse models for these psychiatric diseases display similar cognitive impairments to those observed in human patients. The hippocampi of these mice possess a conserved… CONTINUE READING
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Paper presented at the 41st Annual Meeting of the Society for Neuroscience, Washington, DC

  • K Takao, H Hagihara, K Ohira, K Toyama, T Takagi, S Ishii
  • 2011

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