Detection of alternative splice variants at the proteome level in Aspergillus flavus.

@article{Chang2010DetectionOA,
  title={Detection of alternative splice variants at the proteome level in Aspergillus flavus.},
  author={Kung-Yen Chang and D. Ryan Georgianna and Steffen Heber and Gary A. Payne and David C Muddiman},
  journal={Journal of proteome research},
  year={2010},
  volume={9 3},
  pages={1209-17}
}
Identification of proteins from proteolytic peptides or intact proteins plays an essential role in proteomics. Researchers use search engines to match the acquired peptide sequences to the target proteins. However, search engines depend on protein databases to provide candidates for consideration. Alternative splicing (AS), the mechanism where the exon of pre-mRNAs can be spliced and rearranged to generate distinct mRNA and therefore protein variants, enable higher eukaryotic organisms, with… CONTINUE READING

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