Detection of acute nervous system injury with advanced diffusion-weighted MRI: a simulation and sensitivity analysis.

@article{Skinner2015DetectionOA,
  title={Detection of acute nervous system injury with advanced diffusion-weighted MRI: a simulation and sensitivity analysis.},
  author={Nathan P. Skinner and Shekar Kurpad and Brian D. Schmit and Matthew Budde},
  journal={NMR in biomedicine},
  year={2015},
  volume={28 11},
  pages={1489-506}
}
Diffusion-weighted imaging (DWI) is a powerful tool to investigate the microscopic structure of the central nervous system (CNS). Diffusion tensor imaging (DTI), a common model of the DWI signal, has a demonstrated sensitivity to detect microscopic changes as a result of injury or disease. However, DTI and other similar models have inherent limitations that reduce their specificity for certain pathological features, particularly in tissues with complex fiber arrangements. Methods such as double… CONTINUE READING
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