Detection of activated leukocyte cell adhesion molecule in the serum of breast cancer patients and implications for prognosis.

@article{Witzel2012DetectionOA,
  title={Detection of activated leukocyte cell adhesion molecule in the serum of breast cancer patients and implications for prognosis.},
  author={Isabell D. Witzel and Christine Schroeder and Volkmar Mueller and Hilke Zander and Michael Tachezy and Maike Ihnen and F. J{\"a}nicke and Karin Milde-Langosch},
  journal={Oncology},
  year={2012},
  volume={82 6},
  pages={305-12}
}
OBJECTIVE Conflicting results have been reported about activated leukocyte cell adhesion molecule (ALCAM) expression in breast cancer and its prognostic value. Little is known about the role of ALCAM levels in the serum of breast cancer patients. METHODS We analyzed soluble ALCAM (sALCAM) levels in the serum of 157 primary breast cancer patients and 48 healthy women by ELISA. In addition, we determined ALCAM protein expression by Western blot analysis (n = 120) and mRNA expression by cDNA… CONTINUE READING
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