Detection of TMPRSS2-ERG fusion transcripts and prostate cancer antigen 3 in urinary sediments may improve diagnosis of prostate cancer.

@article{Hessels2007DetectionOT,
  title={Detection of TMPRSS2-ERG fusion transcripts and prostate cancer antigen 3 in urinary sediments may improve diagnosis of prostate cancer.},
  author={D. Scott Hessels and Frank P. Smit and Gerald W Verhaegh and Johannes Alfred Witjes and Erik Bastiaan Cornel and Jack A Schalken},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2007},
  volume={13 17},
  pages={5103-8}
}
PURPOSE Early detection of prostate cancer can increase the curative success rate for prostate cancer. We studied the diagnostic usefulness of TMPRSS2-ERG fusion transcripts as well as the combination of prostate cancer antigen 3 (PCA3) RNA and TMPRSS2-ERG fusion transcripts in urinary sediments after digital rectal examination (DRE). EXPERIMENTAL DESIGN A total of 78 men with prostate cancer-positive biopsies and 30 men with prostate cancer-negative biopsies were included in this study… CONTINUE READING

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TMPRSS 2 : ERG gene fusion associatedwith lethal prostate cancer in a watchfulwaiting cohort

  • D Hessels, GW Verhaegh, JA Schalken, JA Witjes
  • Oncogene
  • 2007

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