Detection of Staphylococcus aureus by functional gold nanoparticle-based affinity surface-assisted laser desorption/ionization mass spectrometry.

@article{Lai2015DetectionOS,
  title={Detection of Staphylococcus aureus by functional gold nanoparticle-based affinity surface-assisted laser desorption/ionization mass spectrometry.},
  author={Hong-Zheng Lai and Sin-Ge Wang and Ching-Yi Wu and Yu-Chie Chen},
  journal={Analytical chemistry},
  year={2015},
  volume={87 4},
  pages={
          2114-20
        }
}
Staphylococcus aureus is one of the common pathogenic bacteria responsible for bacterial infectious diseases and food poisoning. This study presents an analytical method based on the affinity nanoprobe-based mass spectrometry that enables detection of S. aureus in aqueous samples. A peptide aptamer DVFLGDVFLGDEC (DD) that can recognize S. aureus and methicillin-resistant S. aureus (MRSA) was used as the reducing agent and protective group to generate DD-immobilized gold nanoparticles (AuNPs@DD… CONTINUE READING
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