Detection of Pneumocystis carinii by DNA amplification in patients with connective tissue diseases: re-evaluation of clinical features of P. carinii pneumonia in rheumatic diseases.

@article{Saito2004DetectionOP,
  title={Detection of Pneumocystis carinii by DNA amplification in patients with connective tissue diseases: re-evaluation of clinical features of P. carinii pneumonia in rheumatic diseases.},
  author={Kensuke Saito and Shingo Nakayamada and Kazuhisa Nakano and Mikiko Tokunaga and Shizuyo Tsujimura and Kiyoshi Nakatsuka and Taiji Adachi and Yoshiya Tanaka},
  journal={Rheumatology},
  year={2004},
  volume={43 4},
  pages={479-85}
}
OBJECTIVES We evaluated the polymerase chain reaction (PCR) detection of Pneumocystis carinii DNA in induced sputum of patients with connective tissue diseases and assessed the clinical features of patients positive for P. carinii. METHODS Sputum was induced by nebulization in 29 in-patients with various connective tissue diseases who presented with symptoms suggestive of P. carinii pneumonia (PCP), and was examined by PCR. RESULTS Detection of P. carinii DNA by PCR was significantly more… CONTINUE READING
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