Detection of NaCl and KCl in TRPV1 knockout mice.

@article{Ruiz2006DetectionON,
  title={Detection of NaCl and KCl in TRPV1 knockout mice.},
  author={C J G{\'o}mez Ruiz and Stephanie Gutknecht and Eugene R Delay and Sue C Kinnamon},
  journal={Chemical senses},
  year={2006},
  volume={31 9},
  pages={813-20}
}
Both amiloride-sensitive and -insensitive mechanisms contribute to NaCl taste transduction. The amiloride-sensitive mechanism relies on the epithelial Na(+) channel ENaC, which is widely expressed on the apical membrane of fungiform taste cells. The amiloride-insensitive mechanism, which predominates in circumvallate and foliate taste buds, was recently reported to involve a variant of the nonselective cation channel TRPV1. We performed 2-bottle preference and threshold experiments with TRPV1… CONTINUE READING
36 Citations
28 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 36 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 28 references

The effect of amiloride on operantly conditioned performance in an NaCl taste detection task and NaCl preference in C57BL/6J mice

  • S Eylam, Spector AC.
  • Behav Neurosci 116:149–59.
  • 2002

Similar Papers

Loading similar papers…