Detection of Minimal Residual Disease in T-cell Acute Lymphoblastic Leukemia Using Polymerase Chain Reaction Predicts Impending Relapse

  • TGcpClTGGGG G ACTTTTDIKTCTTGGGGAACT TCGGCAT ACmTGTGCTClTGGGGAACT GGmGGG, N D d N TACTGTGCePTTAG GAAATAGT TACTGTGCCTTTA ACGTTCTTG CCTTAACCCC TACTGTGCCT ATCAGG, +6 authors CTTGACAGCACAACTC TGTGCTCITGGG A CTT TAACTC GGGG CTCGTACACCCACA AACTC
  • Published 2003
After achieving remission, approximately one-third of patients with T-cell acute lymphoblastic leukemia (T-ALL) relapse due to the resurgence of residual leukemic cells that cannot be detected in remission by morphologic methods. Thus, the early detection of residual disease is highly desirable to monitor the efficacy of therapy, or to institute an… (More)