Detection of Inflammasome Activation and Pyroptotic Cell Death in Murine Bone Marrow-derived Macrophages.

@article{Hartigh2018DetectionOI,
  title={Detection of Inflammasome Activation and Pyroptotic Cell Death in Murine Bone Marrow-derived Macrophages.},
  author={Andreas B. den Hartigh and Susan L Fink},
  journal={Journal of visualized experiments : JoVE},
  year={2018},
  volume={135}
}
Inflammasomes are innate immune signaling platforms that are required for the successful control of many pathogenic organisms, but also promote inflammatory and autoinflammatory diseases. Inflammasomes are activated by cytosolic pattern recognition receptors, including members of the NOD-like receptor (NLR) family. These receptors oligomerize upon the… CONTINUE READING