Detection of Human papillomavirus and cellular regulators p16INK4a, p53, and NF-kappaB in penile cancer cases in Kenya.

Abstract

Human papillomavirus (HPV) E6 and E7 gene products play a central role in the induction of benign proliferation and malignant transformation by interacting with several cellular regulatory proteins such as p53, p16(INK4a), and nuclear factor kappaB (NF-kappaB). In this study, HPV DNA was detected by in situ hybridization (ISH) and p53, p16(INK4a), and NF… (More)

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Cite this paper

@article{Senba2009DetectionOH, title={Detection of Human papillomavirus and cellular regulators p16INK4a, p53, and NF-kappaB in penile cancer cases in Kenya.}, author={Masachika Senba and Nathan G Buziba and Nozomu Mori and Atsuyuki Wada and Shin-kichi Irie and Kanan Toriyama}, journal={Acta virologica}, year={2009}, volume={53 1}, pages={43-8} }