Detection of Human Papillomavirus DNA in Anal Intraepithelial Neoplasia and Anal Cancer1


Forty anal paraffin-embedded tissue specimens from 24 subjects »ere studied for the presence of human papillomavirus (HPV) types 6, 11, 16, 18, 31, and 33, herpes simplex virus (HSV), Epstein-Barr virus, and cytomegalovirus DNA by using the polymerase chain reaction. These tissues ranged from histologically normal to invasive squamous cell carcinoma. HPV… (More)


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