Detection of Helicobacter pylori in oral aphthous ulcers.

  title={Detection of Helicobacter pylori in oral aphthous ulcers.},
  author={Catalena Birek and Ramesh M Grandhi and Karen L McNeill and David D. Singer and Giuseppe Ficarra and Gregory D. Bowden},
  journal={Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology},
  volume={28 5},
A causative role for Helicobacter pylori (H. pylori) in the pathogenesis of oral mucosal ulcerations has been suggested previously. We have adopted the polymerase chain reaction (PCR) as a rapid and sensitive means to detect H. pylori in swabs of recurrent oral aphthous ulcers and in samples of other oral sites. Of the oral aphthous ulcer samples, 32 (71.8%) were found to be positive, while the saliva and plaque samples (most of them taken from the patients with aphthous ulcers) were… CONTINUE READING


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