Detection of HPV DNA in oral carcinoma using polymerase chain reaction together with in situ hybridization.

@article{Miller1994DetectionOH,
  title={Detection of HPV DNA in oral carcinoma using polymerase chain reaction together with in situ hybridization.},
  author={Craig S. Miller and M S Zeuss and Dean K White},
  journal={Oral surgery, oral medicine, and oral pathology},
  year={1994},
  volume={77 5},
  pages={480-6}
}
This study determined the prevalence of human papillomavirus 16/18 DNA in deparaffinized oral carcinoma specimens on slides with the use of the different sensitivities of in situ hybridization and a technique that combines polymerase chain reaction and in situ hybridization. Human papillomavirus DNA was not detected in the 30 biopsy specimens analyzed by in situ hybridization alone using biotinylated DNA probes specific for human papillomavirus 16/18. Twenty of 30 specimens (66.7%) were found… CONTINUE READING
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