Detection of HLA-DR associated PLT determinants by alloreactive lymphocyte clones

@article{AdrianaZeeviPh1983DetectionOH,
  title={Detection of HLA-DR associated PLT determinants by alloreactive lymphocyte clones},
  author={D. AdrianaZeeviPh. and Kathy Armen and Christi Scheffel and Ren{\'e} J. Duquesnoy},
  journal={Immunogenetics},
  year={1983},
  volume={18},
  pages={205-220}
}
This study deals with alloreactive T-cell clones which recognize cellular determinants associated with HLA-DR antigens. Two clones, CB55 and DS56, exhibited a PLT specificity that was perfectly associated with DR5. On the other hand, clones CB7, DS 1 and HS 1 showed PLT reactivity with approximately one-half of the DR5 positive cells and none of the DR5 negative cells, whereas clone MD4 largely reacted with the other half of DR5 positive cells. Another MLR culture generated two alloreactive… CONTINUE READING