Detection of HCV RNA in the peripheral blood mononuclear cells of serum HCV RNA-negative Egyptian patients under interferon treatment.

@article{Zayed2010DetectionOH,
  title={Detection of HCV RNA in the peripheral blood mononuclear cells of serum HCV RNA-negative Egyptian patients under interferon treatment.},
  author={Rania A Zayed and Eman Rushdy and Doa'a A. Saleh},
  journal={The American journal of the medical sciences},
  year={2010},
  volume={340 6},
  pages={435-8}
}
INTRODUCTION Despite recent success after the introduction of combination therapy with interferon (IFN)-α and ribavirin, approximately 60% of patients with hepatitis C virus (HCV) genotype 4 fail to respond. Resistance to antiviral therapy remains a serious problem in the management of chronic hepatitis C. In most patients, HCV RNA could be detected in peripheral blood mononuclear cell (PBMC). OBJECTIVE The authors aimed to investigate the predictive value of HCV RNA in PBMC of patients with… CONTINUE READING
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