Detection of HBV DNA by PCR and its application in clinical transfusion

@article{Li2018DetectionOH,
  title={Detection of HBV DNA by PCR and its application in clinical transfusion},
  author={Shunqing Li},
  journal={Reports in Clinical Studies and Medicine},
  year={2018}
}
  • Shunqing Li
  • Published 27 December 2018
  • Medicine
  • Reports in Clinical Studies and Medicine
 This study was to detect the hepatitis B virus (HBV) DNA copies in patients through blood transfusions; recessive carriers with HBsAg negative but HBV DNA positive were further studied to see the content and distribution of HBV in patients, and provide evidence for the clinical treatment. A total of 532 blood samples collected from July 2014 to July 2015 were tested for HBV-DNA viral load and hepatitis B serological markers using quantitative Polymerase Chain Reaction (qPCR) and serologic test… 

References

SHOWING 1-5 OF 5 REFERENCES
Application of NAT testing for HBV,HCV and HIV in clinical blood transfusion
TLDR
Screening of blood donors and blood recipients using the technology of NAT could further reduce blood transfusion safety risk and avoid medical disputes caused by transfusion transmitted diseases.
Occult hepatitis B infection and HBV replicative activity in patients with cryptogenic cause of hepatocellular carcinoma
TLDR
The low intrahepatic HBV DNA and pgRNA levels indicated that persistent viral replication and possibly HBV integration are the likely causes of HCC in OBI patients.
QUANTIFICATION OF HBV DNA AND ITS IMPACT ON VIRAL LOAD MONITORING
TLDR
This study includes the ease, reliability and sensitivity of HBV DNA quantification by RT PCRand, and its clinical significance in viral load monitoring.
Prevalence of antibodies to hepatitis B core antigen and occult hepatitis B virus infections in Korean blood donors
BACKGROUND: This study was performed to determine the prevalence of antibodies to hepatitis B core antigen (anti‐HBc) among Korean blood donors and frequencies of hepatitis B virus (HBV) DNA and
Novel Subgenotypes of Hepatitis B Virus Genotypes C and D in Papua, Indonesia
TLDR
Two novel HBV subgenotypes are proposed, HBV/C6 andHBV/D6, the first of which is the most prevalent subgenotype of HBV in Papua, Indonesia, possibly representing a unique antigenic group (provisionally referred to as adrq indeterminate).