Detection of H5 avian influenza viruses by antigen-capture enzyme-linked immunosorbent assay using H5-specific monoclonal antibody.

@article{He2007DetectionOH,
  title={Detection of H5 avian influenza viruses by antigen-capture enzyme-linked immunosorbent assay using H5-specific monoclonal antibody.},
  author={Qigai He and Sumathy Velumani and Qingyun Du and Chee Wee Lim and F. K. Ng and Ruben O. Donis and Jimmy Kwang},
  journal={Clinical and vaccine immunology : CVI},
  year={2007},
  volume={14 5},
  pages={617-23}
}
The unprecedented spread of highly pathogenic avian influenza virus subtype H5N1 in Asia and Europe is threatening animals and public health systems. Effective diagnosis and control management are needed to control the disease. To this end, we developed a panel of monoclonal antibodies (MAbs) against the H5N1 avian influenza virus (AIV) and implemented an antigen-capture enzyme-linked immunosorbent assay (AC-ELISA) to detect the H5 viral antigen. Mice immunized with denatured hemagglutinin (HA… CONTINUE READING