Detection of Glycosaminoglycans using Positive CEST approach

Abstract

Introduction CEST contrast employs Chemical Exchange Saturation Transfer to generate contrast in MRI images. It is based on the selective presaturation of the small pool of exchanging protons and can be switched "on" and "off" using suitable RF irradiation (1). Recently, CEST was applied to detect glycosaminoclycans (GAGs) in articular cartilage and… (More)

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