Detection of Genes with Atypical Nucleotide Sequence in Microbial Genomes

@article{Hooper2001DetectionOG,
  title={Detection of Genes with Atypical Nucleotide Sequence in Microbial Genomes},
  author={Sean D. Hooper and Otto G. Berg},
  journal={Journal of Molecular Evolution},
  year={2001},
  volume={54},
  pages={365-375}
}
Along the gene, nucleotides in various codon positions tend to exert a slight but observable influence on the nucleotide choice at neighboring positions. Such context biases are different in different organisms and can be used as genomic signatures. In this paper, we will focus specifically on the dinucleotide composed of a third codon position nucleotide and its succeeding first position nucleotide. Using the 16 possible dinucleotide combinations, we calculate how well individual genes conform… 
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