Detection of DNA damages and repair in human culture cells with simulated space radiation.

Abstract

DNA damages and its repair of cultured WI38 human fibroblast cells and T98G human glioblastoma cells were studied by exposing to carbon ion beams of HIMAC accelerator. The exposed cells were incubated at 37 degrees C for appropriate intervals and the damages were analyzed by alkaline comet assay and quantitative RT-PCR with p53 mRNA. Highly inhomogeneous… (More)

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@article{Nagaoka1999DetectionOD, title={Detection of DNA damages and repair in human culture cells with simulated space radiation.}, author={Shoji Nagaoka and Toru Nakano and Shigeatsu Endo and Tomoko Onizuka and Yumiko Kagawa and Kazunobu Fujitaka and Kazunori Ohnishi and Akira Takahashi and Takeo Ohnishi}, journal={Acta astronautica}, year={1999}, volume={44 7-12}, pages={561-7} }