• Mathematics, Medicine, Computer Science
  • Published in
    Journal of Computational…
    2017
  • DOI:10.1089/cmb.2017.0037

Detection of Complexes in Biological Networks Through Diversified Dense Subgraph Mining

@article{Ma2017DetectionOC,
  title={Detection of Complexes in Biological Networks Through Diversified Dense Subgraph Mining},
  author={Xiuli Ma and Guangyu Zhou and Jingbo Shang and Jingjing Wang and Jian Peng and Jiawei Han},
  journal={Journal of computational biology : a journal of computational molecular cell biology},
  year={2017},
  volume={24 9},
  pages={
          923-941
        }
}
Protein-protein interaction (PPI) networks, providing a comprehensive landscape of protein interaction patterns, enable us to explore biological processes and cellular components at multiple resolutions. For a biological process, a number of proteins need to work together to perform a job. Proteins densely interact with each other, forming large molecular machines or cellular building blocks. Identification of such densely interconnected clusters or protein complexes from PPI networks enables… CONTINUE READING
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