Detection of Colorectal Serrated Polyps by Stool DNA Testing: Comparison with Fecal Immunochemical Testing for Occult Blood (FIT)

@inproceedings{Heigh2014DetectionOC,
  title={Detection of Colorectal Serrated Polyps by Stool DNA Testing: Comparison with Fecal Immunochemical Testing for Occult Blood (FIT)},
  author={Russell I. Heigh and Tracy C. Yab and William R Taylor and Fareeda Taher Nazer Hussain and Thomas C. Smyrk and Douglas W. Mahoney and Michael J. Domanico and Barry M. Berger and Graham P. Lidgard and David A. Ahlquist},
  booktitle={PloS one},
  year={2014}
}
OBJECTIVES Precursors to 1/3 of colorectal cancer (CRC), serrated polyps have been under-detected by screening due to their inconspicuous, non-hemorrhagic, and proximal nature. A new multi-target stool DNA test (multi-target sDNA) shows high sensitivity for both CRC and advanced adenomas. Screen detection of serrated polyps by this approach requires further validation. We sought to assess and compare noninvasive detection of sessile serrated polyps (SSP) ≥ 1 cm by sDNA and an occult blood fecal… CONTINUE READING