Detection of Alzheimer's disease signature in MR images seven years before conversion to dementia: Toward an early individual prognosis.

@article{Coup2015DetectionOA,
  title={Detection of Alzheimer's disease signature in MR images seven years before conversion to dementia: Toward an early individual prognosis.},
  author={Pierrick Coup{\'e} and Vladimir S Fonov and Charlotte Bernard and Azar Zandifar and Simon Fristed Eskildsen and Catherine Helmer and Jos{\'e} V. Manj{\'o}n and H{\'e}l{\`e}ne Amieva and J F Dartigues and Mich{\`e}le Allard and Gwenaelle Catheline and D. Louis Collins},
  journal={Human brain mapping},
  year={2015},
  volume={36 12},
  pages={4758-70}
}
Finding very early biomarkers of Alzheimer's Disease (AD) to aid in individual prognosis is of major interest to accelerate the development of new therapies. Among the potential biomarkers, neurodegeneration measurements from MRI are considered as good candidates but have so far not been effective at the early stages of the pathology. Our objective is to investigate the efficiency of a new MR-based hippocampal grading score to detect incident dementia in cognitively intact patients. This new… CONTINUE READING
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Alzheimer's Disease Neuroimaging I. Hierarchical feature representation and multimodal fusion with deep learning for AD/MCI diagnosis

  • Suk H-I, Lee S-W, D Shen
  • 2014
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