Detection of "PNH red cell" populations in hematological disorders using the Sephacryl Gel Test micro typing system.

@article{Meletis1997DetectionO,
  title={Detection of "PNH red cell" populations in hematological disorders using the Sephacryl Gel Test micro typing system.},
  author={J. C. Meletis and Evi Michali and Michalis Samarkos and Konstantinos Konstantopoulos and Christos Meletis and Evangelos Terpos and A Tsimberidou and E Chandrinou and Nikolaos Spanakis and Yiannis Rombos and Gerassimos Alexander Pangalis and X{\'e}nophon A. Yataganas and Dimitris Loukopoulos},
  journal={Leukemia & lymphoma},
  year={1997},
  volume={28 1-2},
  pages={
          177-82
        }
}
Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired clonal disorder characterised by an unusual sensitivity of abnormal red cell population(s) to complement lysis, due to a complete or incomplete defect of various surface molecules, including CD55 and CD59. PNH has been associated with various hematological disorders. Using a newly introduced method, the Sephacryl gel test microtyping system, we investigated the presence of CD55 or CD59 defective red cell populations in several… CONTINUE READING
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