Detection and treatment of congenital hypothyroidism

  title={Detection and treatment of congenital hypothyroidism},
  author={Annette Grueters and Heiko Krude},
  journal={Nature Reviews Endocrinology},
Congenital hypothyroidism is the most frequent endocrine disorder in neonates. Controversy exists regarding the necessity to adjust current screening programs to also diagnose patients with central hypothyroidism or those with mild forms of congenital hypothyroidism, who have high TSH levels but normal T4 and normal T3 levels (also known as 'subclinical hypothyroidism'). Thyroid hormone replacement should start as soon as the diagnosis is confirmed by measurement of elevated TSH and low serum… CONTINUE READING
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