Detection and significance of fluconazole resistance in oropharyngeal candidiasis in human immunodeficiency virus-infected patients.

@article{Revankar1996DetectionAS,
  title={Detection and significance of fluconazole resistance in oropharyngeal candidiasis in human immunodeficiency virus-infected patients.},
  author={Sanjay G Revankar and William R. Kirkpatrick and R K Mcatee and Olga P Dib and Annette W. Fothergill and Spencer W. Redding and Michael G. Rinaldi and Thomas F. Patterson},
  journal={The Journal of infectious diseases},
  year={1996},
  volume={174 4},
  pages={821-7}
}
The epidemiology and clinical significance of fluconazole resistance were assessed in a cohort of advanced human immunodeficiency virus (HIV)-infected patients with recurrent oropharyngeal candidiasis. Fifty patients were prospectively evaluated using a novel method of detecting fluconazole resistance with chromogenic media containing fluconazole; results were confirmed with macrobroth testing. Resistant yeasts, defined as MICs > or = 8 micrograms/mL, were detected in 16 (32%) of 50 patients: 7… CONTINUE READING

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