Detection and quantitation of human papillomavirus DNA in primary tumour and lymph nodes of patients with early stage cervical carcinoma.

@article{Chan2005DetectionAQ,
  title={Detection and quantitation of human papillomavirus DNA in primary tumour and lymph nodes of patients with early stage cervical carcinoma.},
  author={Paul K S Chan and May Mei-Yung Yu and Tak Hong Cheung and Ka-fai To and Keith Wing-kit Lo and Jo Lai Ken Cheung and Joanna H M Tong},
  journal={Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology},
  year={2005},
  volume={33 3},
  pages={201-5}
}
Fifteen Chinese women with early stage cervical squamous cell carcinoma (14 stage IB, one stage IIA) were retrospectively analysed for the correlation between human papillomavirus (HPV) load in primary tumour and the presence of HPV DNA in histologically tumour-free pelvic lymph nodes. HPV16 DNA was detected from majority (12/15) of primary tumours, with a viral load ranging from 12 to 1800 copies per cell. Of the 156 histologically tumour-free pelvic lymph nodes, 41 (26.3%) were positive for… CONTINUE READING

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