Detection and quantification of lipoprotein(a) in the arterial wall of 107 coronary bypass patients.

  title={Detection and quantification of lipoprotein(a) in the arterial wall of 107 coronary bypass patients.},
  author={Matthias Rath and Axel Niendorf and Tjark Reblin and Manfred Dietel and Hans J. Krebber and Ulrike Beisiegel},
  volume={9 5},
The aim of this study was to determine the extent of accumulation of lipoprotein(a) [Lp(a)] in human arterial wall and to define its potential role in atherogenesis. Biopsies routinely taken from the ascending aorta of 107 patients undergoing aortocoronary bypass surgery were analyzed for lipid and lipoprotein parameters, which were then correlated to serum values. A significant positive correlation was established between serum Lp(a) and arterial wall apolipoprotein (apo)(a) by enzyme-linked… CONTINUE READING


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