Detection and quantification of acidic drug residues in South African surface water using gas chromatography-mass spectrometry.

@article{Gumbi2017DetectionAQ,
  title={Detection and quantification of acidic drug residues in South African surface water using gas chromatography-mass spectrometry.},
  author={Bhekumuzi P Gumbi and Brenda Moodley and Grace Birungi and Patrick G Ndungu},
  journal={Chemosphere},
  year={2017},
  volume={168},
  pages={1042-1050}
}
A method was optimized for derivatization, separation, detection and quantification of salicylic acid, acetylsalicylic acid, nalidixic acid, ibuprofen, phenacetin, naproxen, ketoprofen, meclofenamic acid and diclofenac in surface water using gas chromatography-mass spectrometry. For most of the acidic drugs, recovery was in the range 60-110% and the percent standard deviation was below 15% for the entire method, with limits of detection ranging from 0.041 to 1.614 μg L-1. The developed method… CONTINUE READING

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