Detection and phylogenetic assessment of conserved synteny derived from whole genome duplications.

@article{Kuraku2012DetectionAP,
  title={Detection and phylogenetic assessment of conserved synteny derived from whole genome duplications.},
  author={Shigehiro Kuraku and Axel Meyer},
  journal={Methods in molecular biology},
  year={2012},
  volume={855},
  pages={
          385-95
        }
}
Identification of intragenomic conservation of gene compositions in multiple chromosomal segments led to evidence of whole genome (WGDs) duplications. The process by which WGDs have been maintained and decayed provides us with clues for understanding how the genome evolves. In this chapter, we summarize current understanding of phylogenetic distribution and evolutionary impact of WGDs, introduce basic procedures to detect conserved synteny, and discuss typical pitfalls, as well as biological… 

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An important mechanism for the evolution of phenotypic complexity, diversity and innovation, and the origin of novel gene functions is the duplication of genes and entire genomes. Recent phylogenomic
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