Detection and measurement of MeIQx in human urine after ingestion of a cooked meat meal.

@article{Murray1989DetectionAM,
  title={Detection and measurement of MeIQx in human urine after ingestion of a cooked meat meal.},
  author={Stephen G. Murray and Nigel J. Gooderham and Alan R Boobis and Donald Selwyn Davies},
  journal={Carcinogenesis},
  year={1989},
  volume={10 4},
  pages={
          763-5
        }
}
A gas chromatographic-mass spectrometric assay has been developed for the measurement of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in urine. The method employs capillary column gas chromatography, electron capture negative-ion chemical ionization mass spectrometry, a stable isotope-labelled analogue of MeIQx as internal standard and has a limit of detection of 5 pg MeIQx/ml urine. Six subjects consumed a fried beef meal and urine was collected before and after this event. While no… CONTINUE READING
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