Detection and clinical outcome of urinary bladder cancer with 5-aminolevulinic acid-induced fluorescence cystoscopy : A multicenter randomized, double-blind, placebo-controlled trial.

@article{Stenzl2011DetectionAC,
  title={Detection and clinical outcome of urinary bladder cancer with 5-aminolevulinic acid-induced fluorescence cystoscopy : A multicenter randomized, double-blind, placebo-controlled trial.},
  author={Arnulf Stenzl and Hannes Penkoff and Elfriede Dajc-Sommerer and Andreas Zumbraegel and Lorenz Hoeltl and Michael Scholz and Claus Riedl and Josef Bugelnig and Alfred Hobisch and Maximilian Burger and Gregor Mikuz and Uwe Pichlmeier},
  journal={Cancer},
  year={2011},
  volume={117 5},
  pages={938-47}
}
BACKGROUND The medical community lacks results from prospective controlled multicenter studies of the diagnostic efficacy of 5-aminolevulinic acid (5-ALA) cystoscopy on tumor recurrence in patients with superficial bladder tumors. METHODS A prospective randomized, double-blind, placebo-controlled study was conducted in 370 patients with nonmuscle-invasive urinary bladder carcinoma who received either 5-ALA (n = 187) or a placebo (n = 183) intravesically before cystoscopy. Each group underwent… CONTINUE READING