Detection and analysis of cancer cells in blood and bone marrow using a rare event imaging system.

@article{Kraeft2000DetectionAA,
  title={Detection and analysis of cancer cells in blood and bone marrow using a rare event imaging system.},
  author={S K Kraeft and R M Sutherland and Laura M. Gravelin and Guangjing Hu and Louis H. Ferland and Paul Richardson and Agnes Elias and Lan Bo Chen},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2000},
  volume={6 2},
  pages={434-42}
}
An automated rare event detection system (Rare Event Imaging System) is described for the recognition of cancer cells that appear at low frequencies (1 in 1 million) in peripheral blood (PB) or bone marrow (BM). The instrumentation includes an automated fluorescence microscope (Nikon Microphot-FXA) with a cooled charge coupled device camera and a 60-MHz Pentium personal computer. Main features of the system are rapid analysis of large microscopic fields, including a total cell count, detection… CONTINUE READING

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