Detection and Toxicity Evaluation of Pyrrolizidine Alkaloids in Medicinal Plants Gynura bicolor and Gynura divaricata Collected from Different Chinese Locations

@article{Chen2017DetectionAT,
  title={Detection and Toxicity Evaluation of Pyrrolizidine Alkaloids in Medicinal Plants Gynura bicolor and Gynura divaricata Collected from Different Chinese Locations},
  author={J. Chen and H. L{\"u} and Lian-xiang Fang and Wei-lin Li and L. Verschaeve and Zheng-tao Wang and N. de Kimpe and Sven Mangelinckx},
  journal={Chemistry & Biodiversity},
  year={2017},
  volume={14}
}
Two edible plants in Southeast Asia, Gynura bicolor and G. divaricata, are not only known to be nutritive but also useful as medicinal herbs. Previous phytochemical investigation of Gynura species showed the presence of hepatotoxic pyrrolizidine alkaloids (PAs), indicating the toxic risk of using these two plants. The present study was designed to analyze the distribution of PA components and tried to evaluate the preliminary toxicity of these two Gynura species. Eight samples of G. bicolor and… Expand
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References

SHOWING 1-10 OF 49 REFERENCES
Assessment of pyrrolizidine alkaloid-induced toxicity in an in vitro screening model.
  • 30
Phytochemical profile, antioxidative and anti-inflammatory potentials of Gynura bicolor DC.
  • 13
Investigation of the antimutagenic effects of selected South African medicinal plant extracts.
  • 83
The anti-hyperglycemic effect of plants in genus Gynura Cass.
  • 39
Chemical Constituents from the Aerial Parts of Gynura Bicolor
  • 12
...
1
2
3
4
5
...