Detection and Prediction of Bioprosthetic Aortic Valve Degeneration

  title={Detection and Prediction of Bioprosthetic Aortic Valve Degeneration},
  author={Timothy R.G. Cartlidge and Mhairi K. Doris and Stephanie Leigh Sellers and Tania Ashwinikumar Pawade and Audrey C. White and Renzo Pessotto and Jacek Kwiecinski and Alison Fletcher and Carlos Cea Alcaide and Christophe Lucatelli and Cameron G. Densem and James H F Rudd and Edwin J. R. van Beek and Adriana Alexandre S. Tavares and Renu Virmani and Daniel S. Berman and Jonathon A. Leipsic and David E. Newby and M. R. Dweck},
  booktitle={Journal of the American College of Cardiology},
BACKGROUND Bioprosthetic aortic valve degeneration is increasingly common, often unheralded, and can have catastrophic consequences. OBJECTIVES The authors sought to assess whether 18F-fluoride positron emission tomography (PET)-computed tomography (CT) can detect bioprosthetic aortic valve degeneration and predict valve dysfunction. METHODS Explanted degenerate bioprosthetic valves were examined ex vivo. Patients with bioprosthetic aortic valves were recruited into 2 cohorts with and… CONTINUE READING
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  • 2018