Detecting strong positive selection in the genome.

@article{Stephan2010DetectingSP,
  title={Detecting strong positive selection in the genome.},
  author={W. Stephan},
  journal={Molecular ecology resources},
  year={2010},
  volume={10 5},
  pages={863-72}
}
New statistical tests have been developed in the past decade that enable us to infer evidence of recent strong positive selection from genome-wide data on single-nucleotide polymorphism and to localize the targets of selection in the genome. Based on these tests, past demographic events that led to distortions of the site-frequency spectrum of variation can be distinguished from selection, in particular if linkage disequilibrium is taken into account. These methods have been successfully… CONTINUE READING

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