Detecting signatures of selection through haplotype differentiation among hierarchically structured populations.

@article{Fariello2013DetectingSO,
  title={Detecting signatures of selection through haplotype differentiation among hierarchically structured populations.},
  author={Maria Ines Fariello and Simon Boitard and Hugo Naya and Magali Sancristobal and Bertrand Servin},
  journal={Genetics},
  year={2013},
  volume={193 3},
  pages={929-41}
}
The detection of molecular signatures of selection is one of the major concerns of modern population genetics. A widely used strategy in this context is to compare samples from several populations and to look for genomic regions with outstanding genetic differentiation between these populations. Genetic differentiation is generally based on allele frequency differences between populations, which are measured by FST or related statistics. Here we introduce a new statistic, denoted hapFLK, which… CONTINUE READING
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