Detecting selection bias in randomized clinical trials.

@article{Berger1999DetectingSB,
  title={Detecting selection bias in randomized clinical trials.},
  author={Vance W. Berger and Derek V. Exner},
  journal={Controlled clinical trials},
  year={1999},
  volume={20 4},
  pages={319-27}
}
Lack of concealment of allocation in randomized clinical trials can invite selection bias, which is the preferential enrollment of specific patients into one treatment group over another. For example, patients more likely to respond may be enrolled only when the next treatment to be assigned is known to be the active treatment, and patients less likely to respond may be enrolled only when the next treatment to be assigned is known to be the control. Despite the fact that selection bias can… CONTINUE READING