Detecting non-coding selective pressure in coding regions

Abstract

Comparative genomics approaches, where orthologous DNA regions are compared and inter-species conserved regions are identified, have proven extremely powerful for identifying non-coding regulatory regions located in intergenic or intronic regions. However, non-coding functional elements can also be located within coding region, as is common for exonic… (More)
DOI: 10.1186/1471-2148-7-S1-S9

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