Detecting latent tuberculosis infection in hemodialysis patients: a head-to-head comparison of the T-SPOT.TB test, tuberculin skin test, and an expert physician panel.

@article{Passalent2007DetectingLT,
  title={Detecting latent tuberculosis infection in hemodialysis patients: a head-to-head comparison of the T-SPOT.TB test, tuberculin skin test, and an expert physician panel.},
  author={Laura A Passalent and Kamran Khan and Robert Richardson and Jun Wang and Helen Dedier and Michael Gardam},
  journal={Clinical journal of the American Society of Nephrology : CJASN},
  year={2007},
  volume={2 1},
  pages={68-73}
}
Current guidelines advocate screening hemodialysis patients for latent tuberculosis infection; however, the tuberculin skin test (TST) is believed to be insensitive in this population. This study compared the diagnostic utility of the TST with that of an IFN-gamma assay (T-SPOT.TB) and the clinical consensus of an expert physician panel. A total of 203 patients with ESRD were evaluated for latent tuberculosis infection with the TST, T-SPOT.TB test, and an expert physician panel. Test results… CONTINUE READING

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