Detecting effects of donepezil on visual selective attention using signal detection parameters in Alzheimer's disease.

@article{Foldi2005DetectingEO,
  title={Detecting effects of donepezil on visual selective attention using signal detection parameters in Alzheimer's disease.},
  author={Nancy S. Foldi and Richard E C White and Lynn Schaefer},
  journal={International journal of geriatric psychiatry},
  year={2005},
  volume={20 5},
  pages={485-8}
}
BACKGROUND Attentional function is impaired in Alzheimer's disease (AD). Moreover, attention is mediated by acetylcholine. But, despite the widespread use of acetylcholinesterase inhibitors (AChE-I) to augment available acetylcholine in AD, measures of attentional function have not been used to assess the drug response. OBJECTIVES We hypothesized that as cholinergic augmentation impacts directly on the attentional system, higher-order measures of visual selective attention would be sensitive… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 25 extracted citations

Impaired attention in the 3xTgAD mouse model of Alzheimer's disease: rescue by donepezil (Aricept).

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2011
View 4 Excerpts
Highly Influenced

Cognitive Enhancement

Handbook of Experimental Pharmacology • 2015
View 1 Excerpt

Similar Papers

Loading similar papers…