Detecting differentially expressed genes by relative entropy.

@article{Yan2005DetectingDE,
  title={Detecting differentially expressed genes by relative entropy.},
  author={Xiting Yan and Minghua Deng and Wing Kam Fung and Minping Qian},
  journal={Journal of theoretical biology},
  year={2005},
  volume={234 3},
  pages={
          395-402
        }
}
DNA microarray experiments have generated large amount of gene expression measurements across different conditions. One crucial step in the analysis of these data is to detect differentially expressed genes. Some parametric methods, including the two-sample t-test (T-test) and variations of it, have been used. Alternatively, a class of non-parametric algorithms, such as the Wilcoxon rank sum test (WRST), significance analysis of microarrays (SAM) of Tusher et al. (2001), the empirical Bayesian… CONTINUE READING
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